I'm curious, why is it considered problematic to have an excess of tau in a system? Could you elaborate on the potential negative consequences and explain why it's crucial to maintain a balance or limit its presence? Is there a specific threshold or range that's considered optimal for ensuring smooth operations and minimizing risks in the realm of
cryptocurrency and finance?
5 answers
CryptoWizardry
Tue Aug 20 2024
The presence of soluble abnormal tau and its oligomers within neurons poses a significant threat to their vitality. These pathological proteins are known to inflict damage, ultimately leading to neuronal death and the manifestation of dementia.
BlockchainVisionary
Mon Aug 19 2024
Neurons, in an attempt to safeguard themselves, appear to have developed a defense mechanism against the toxic effects of abnormal tau. This response involves the further polymerization of these harmful proteins.
CryptoVanguard
Mon Aug 19 2024
The result of this polymerization process is the formation of highly aggregated paired helical filaments (PHFs) and neurofibrillary tangles (NFTs). These structures, though potentially inert in nature, can still pose a significant risk to the health of affected neurons.
AltcoinAdventurer
Mon Aug 19 2024
It is hypothesized that the accumulation of PHFs and NFTs within neurons can ultimately lead to a choking effect, impeding the normal functioning of the cell. This obstruction can exacerbate the already stressed state of the neuron, accelerating its demise.
CryptoQueen
Mon Aug 19 2024
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