Can Target deny my return?

I'm curious to know, under what circumstances could Target potentially deny a return? I understand that there are usually policies in place to ensure customer satisfaction, but are there any specific scenarios where they might decline a return? It would be helpful to understand the process and what measures they take to evaluate return requests. Is there a clear-cut guideline or is it more case-by-case basis? I'm looking to gain a better understanding of the return policy at Target.