Cryptocurrency Q&A
What is STAT1 STAT3 gain of function and mechanisms of immune dysregulation?
What is STAT1 STAT3 gain of function and mechanisms of immune dysregulation?
Federica
Wed Oct 30 2024
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5 answers
1208
STAT1 and STAT3 are members of the STAT family of transcription factors. Gain-of-function mutations in these genes lead to immune dysregulation by altering their normal regulatory roles. Specifically, such mutations can result in enhanced or abnormal activation of immune responses, contributing to the development of immune-related diseases.
5 answers
Eleonora
Fri Nov 01 2024
Similarly, the gain of function of the STAT3 protein also triggers immune dysregulation.
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benjamin_brown_entrepreneur
Fri Nov 01 2024
STAT3 GOF diseases are characterized by the over-activation of immune cells.
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Lucia
Fri Nov 01 2024
The gain of function of the STAT1 protein leads to several health issues.
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Valentino
Fri Nov 01 2024
Both STAT1 and STAT3 GOF diseases are genetic conditions that require medical attention.
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alexander_watson_astronaut
Fri Nov 01 2024
When STAT1 becomes overly active, it disrupts the normal functioning of the immune system.
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