Cryptocurrency Q&A What genes does STAT1 activate?

What genes does STAT1 activate?

EmmaWatson EmmaWatson Thu Oct 31 2024 | 6 answers 1202
I'm interested in understanding the function of STAT1 gene. Specifically, I want to know which genes are activated by STAT1. What genes does STAT1 activate?

6 answers

ShintoSanctuary ShintoSanctuary Sat Nov 02 2024
STAT1 possesses the ability to interact with phosphorylated Tyr-440 via its SH2 domain.

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Lorenzo Lorenzo Fri Nov 01 2024
STAT1 then forms dimers through reciprocal SH2-phosphotyrosine interactions.

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GyeongjuGloryDaysFestival GyeongjuGloryDaysFestival Fri Nov 01 2024
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CryptoAlly CryptoAlly Fri Nov 01 2024
This interaction facilitates the phosphorylation of STAT1's Tyr-701 residue by JAKs.

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DigitalBaron DigitalBaron Fri Nov 01 2024
Once phosphorylated, STAT1 undergoes a conformational change.

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