STAT1 and STAT2 are proteins that belong to the STAT family, which is involved in signal transduction and transcriptional activation. They play key roles in the interferon JAK-STAT pathway, mediating type I and type III interferon signaling and essential for the cellular antiviral response and adaptive immunity.
7 answers
ethan_lewis_journalist
Mon Nov 04 2024
In addition to their antiviral functions, STAT1 and STAT2 are also essential components of adaptive immunity.
Claudio
Mon Nov 04 2024
They work in conjunction with other proteins to ensure the proper functioning of the immune system.
GyeongjuGloryDaysFestivalJoy
Mon Nov 04 2024
One such protein they associate with is the interferon regulatory factor 9 (IRF9).
KpopHarmonySoulMateRadiance
Mon Nov 04 2024
STAT1 and STAT2 proteins play a crucial role in the signaling pathways of type I and type III interferons (IFNs).
AzureWave
Mon Nov 04 2024
Together, STAT1, STAT2, and IRF9 form a complex transcription factor known as ISGF3.