I'm interested in understanding the activation process of STAT1. Could you explain what happens during the activation of STAT1 and its role in cellular signaling?
7 answers
CryptoTitan
Mon Nov 04 2024
There are three main kinases involved in this process: Jak1, Jak2, and Tyk2.
KpopMelody
Mon Nov 04 2024
These kinases play a crucial role in the signaling pathway that leads to STAT1 activation.
OliviaTaylor
Mon Nov 04 2024
The activation process of STAT1 begins with the interaction between type I or type II IFNs and their respective receptors.
GwanghwamunGuardian
Mon Nov 04 2024
Once activated, the kinases phosphorylate STAT1 at a specific amino acid residue, Tyr701.
Lucia
Mon Nov 04 2024
This binding event triggers a cascade of reactions within the cell.