I'm currently studying signal transducer and activator of transcription, specifically STAT1 and STAT2. I want to understand what they are, their functions, and how they differ from each other.
6 answers
Michele
Mon Nov 11 2024
These proteins are indispensable for the cellular antiviral response, which is vital for protecting cells from viral infections.
MoonlitCharm
Mon Nov 11 2024
STAT1 and STAT2 proteins play crucial roles in the signaling pathways of type I and type III interferons (IFNs).
Giulia
Sun Nov 10 2024
ISGF3 is a heterotrimeric transcription factor complex that plays a significant role in regulating gene expression in response to IFN signaling.
Emanuele
Sun Nov 10 2024
In addition to their antiviral functions, STAT1 and STAT2 are also essential components of adaptive immunity.
SsamziegangSerenadeMelodyHarmony
Sun Nov 10 2024
They work closely with another protein, IFN regulatory factor 9 (IRF9), to form a complex structure.