What is the composition of SLN?

SLNs, or Solid Lipid Nanoparticles, are intricate formulations crafted from a blend of essential components. At their core, they consist of lipids, which serve as the foundational matrix for encapsulating active pharmaceutical ingredients (APIs).

Surfactants play a pivotal role in the formulation of SLNs, as they assist in stabilizing the nanoparticles and ensuring their uniform distribution. Co-surfactants, meanwhile, enhance the effectiveness of the surfactant, further refining the structure and functionality of the nanoparticles.

Beyond these foundational components, SLNs can also incorporate a range of additional excipients to tailor their properties. Antioxidants, for instance, protect the encapsulated API from degradation, while preservatives safeguard against microbial contamination.

Adhesives and viscosity enhancers contribute to the overall stability and delivery profile of SLNs, ensuring they remain intact during administration and optimizing their interaction with biological tissues. Absorption-enhancing agents, on the other hand, facilitate the transport of the encapsulated API across biological membranes.

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