Is it easier to come when you're high?

I'm curious, does being under the influence of psychoactive substances actually make it easier to achieve certain states of mind or experiences, such as the so-called "coming" you've mentioned? I'm interested in understanding the potential psychological and physiological mechanisms behind this phenomenon, if any exist at all. Is there any scientific evidence to support this claim, or is it more of a subjective experience that varies from person to person? I'd love to hear your thoughts on this topic as a professional in the field of cryptocurrency and finance, especially if you have any insights into how this might relate to decision-making and risk-taking in the context of financial investments.