How common is fio?

Fibrogenesis imperfecta ossium, commonly abbreviated as FIO, is an exceptionally uncommon disorder that affects the skeletal system. It is classified as an acquired metabolic bone disease, meaning it arises during one's lifetime rather than being present from birth.

The primary characteristic of FIO lies in its connection to a defect in collagen, a crucial protein that provides structural support to bones and other connective tissues. This collagen abnormality within the bone matrix significantly impacts the strength and integrity of the bones.

In addition to medical treatment, individuals with FIO must also take special precautions in their daily lives to prevent accidental injuries that could lead to fractures. This may include avoiding high-impact activities and wearing protective gear when necessary.

The collagen defect in FIO results in a weakening of the bones, making them highly susceptible to spontaneous fractures. These fractures can occur without any apparent cause or trauma, posing a significant challenge for individuals affected by this rare disease.

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