What is the encapsulation efficiency of SLN?

In a particular instance, the SLN formulation achieved an EE of 70.56%, indicating a moderate to high level of encapsulation efficiency. This value suggests that a significant portion of the active ingredient was successfully incorporated within the SLN matrix.

Solid lipid nanoparticles (SLNs) exhibit a diverse range of particle sizes, typically ranging from approximately 163 to 369 nanometers. This variation in size is attributed to the specific lipid composition and surfactant utilized during their formulation.

The entrapment efficiency (EE) of SLNs, a crucial parameter reflecting their ability to encapsulate active ingredients, varies significantly between 51.25% and 90.08%. This wide range underscores the impact of formulation variables on the overall performance of these nanoparticles.

Alongside its EE, the diameter of this particular SLN was measured to be 217.3 nanometers. This size falls within the typical range observed for SLNs, making it suitable for various applications where nanoparticle size is a critical factor.

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