I'm interested in finding out the specific locations of the phosphorylation sites within the STAT1 protein. Can you provide me with this information?
7 answers
KimchiQueenCharm
Wed Nov 06 2024
Following phosphorylation on Y701, Stat1 undergoes nuclear accumulation.
Eleonora
Wed Nov 06 2024
Nuclear accumulation is a necessary step for Stat1 to exert its transcriptional activity.
Valentina
Wed Nov 06 2024
Activation of Stat1 is a crucial process that involves phosphorylation on a specific residue.
CryptoTitanGuard
Wed Nov 06 2024
However, for full transcriptional activity and biological function, Stat1 must undergo additional phosphorylation.
Bianca
Wed Nov 06 2024
This additional phosphorylation occurs on S727, and it is induced by interferon (IFN).