Cryptocurrency Q&A Where are the phosphorylation sites in STAT1?

Where are the phosphorylation sites in STAT1?

SilenceSolitude SilenceSolitude Mon Nov 04 2024 | 7 answers 1727
I'm interested in finding out the specific locations of the phosphorylation sites within the STAT1 protein. Can you provide me with this information? Where are the phosphorylation sites in STAT1?

7 answers

KimchiQueenCharm KimchiQueenCharm Wed Nov 06 2024
Following phosphorylation on Y701, Stat1 undergoes nuclear accumulation.

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Eleonora Eleonora Wed Nov 06 2024
Nuclear accumulation is a necessary step for Stat1 to exert its transcriptional activity.

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Valentina Valentina Wed Nov 06 2024
Activation of Stat1 is a crucial process that involves phosphorylation on a specific residue.

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CryptoTitanGuard CryptoTitanGuard Wed Nov 06 2024
However, for full transcriptional activity and biological function, Stat1 must undergo additional phosphorylation.

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Bianca Bianca Wed Nov 06 2024
This additional phosphorylation occurs on S727, and it is induced by interferon (IFN).

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