Cryptocurrency Q&A
Why do 90% drugs fail?
Why do 90% drugs fail?
MysticRainbow
Tue Dec 10 2024
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5 answers
825
I'm curious about the high failure rate of drugs during development. Specifically, why do approximately 90% of drugs fail to make it through the process and get approved for use by patients?
5 answers
Nicola
Thu Dec 12 2024
Poor drug-like properties are the third reason, contributing to 10% to 15% of the failures. This refers to drugs that may not have the ideal characteristics for effective treatment or may not be suitable for human use.
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Lucia
Thu Dec 12 2024
Clinical trial data from the years 2010 to 2017 has been analyzed to understand the reasons behind the high failure rate of drug development.
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Michele
Thu Dec 12 2024
The fourth reason for clinical failure is the lack of commercial needs and poor strategic planning, accounting for 10% of the failures. This highlights the importance of understanding market demands and developing a robust strategic plan during drug development.
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Nicola
Thu Dec 12 2024
The analysis reveals four primary factors contributing to the 90% clinical failure rate. The first reason is the lack of clinical efficacy, which accounts for 40% to 50% of the failures.
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BonsaiVitality
Thu Dec 12 2024
The second reason is unmanageable toxicity, responsible for approximately 30% of the clinical failures. This indicates that many drugs, despite showing promise in initial stages, are found to have severe side effects during clinical trials.
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