What is the top down approach for IBD?

Inflammatory Bowel Disease (IBD) can be treated through two distinct approaches. The first method is known as Top-down therapy, which primarily relies on the use of medications such as Infliximab (IFX) or Adalimumab (ADA).

These medications are utilized as the initial line of therapy, either alone or in conjunction with immunomodulators. The Top-down approach aims to swiftly achieve and maintain disease remission by employing potent therapies early on.

Alternatively, there is the Step-up approach to treating IBD. This method involves inducing remission through a series of therapeutic cycles, typically starting with less aggressive treatments and gradually escalating to more potent options if necessary.

Both the Top-down and Step-up approaches have their own sets of advantages and considerations, and the choice between them often depends on the individual patient's condition, disease severity, and response to previous treatments.

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