I'm curious about the duration of GATTEX's effectiveness. Specifically, I want to know the half-life of GATTEX, which indicates how long it takes for the drug's concentration in the body to be reduced to half its initial value.
5 answers
BlockProducer
Sun Oct 27 2024
Teduglutide exhibits a specific pharmacokinetic profile in different populations.
CryptoVisionary
Sat Oct 26 2024
The reduction in half-life suggests a faster clearance rate of the drug in SBS patients, potentially requiring more frequent dosing to maintain therapeutic levels.
CryptoQueenGuard
Sat Oct 26 2024
In healthy individuals, the mean terminal half-life (t1/2) of Teduglutide is approximately 2 hours.
Bianca
Sat Oct 26 2024
This indicates that the drug is eliminated from the body of healthy subjects within a relatively short period after administration.
HanjiArtist
Sat Oct 26 2024
In contrast, the mean terminal half-life of Teduglutide is shortened to 1.3 hours in subjects with short bowel syndrome (SBS).