What is the most profitable trade ever?

Can you enlighten me on the most lucrative trade ever conducted in the realm of finance, particularly focusing on the cryptocurrency sphere? Has there been a singular transaction that has outshone all others in terms of profitability, reshaping the landscape of financial markets and capturing the imagination of investors worldwide? If so, what factors contributed to its unprecedented success, and what lessons can we draw from this groundbreaking trade to inform our own investment strategies?