I'm curious about the rationale behind using Z scores for creating heatmaps. Why is this statistical measure preferred for such visualizations, and what advantages does it offer over other methods?
7 answers
BonsaiLife
Thu Jan 02 2025
A threshold value like 2 or 3 is commonly used to determine which genes show significant expression changes.
ShintoMystic
Thu Jan 02 2025
Genes with a Z-score exceeding a specific threshold are often deemed to be differentially expressed.
CryptoWizard
Wed Jan 01 2025
Another popular visualization tool is the volcano plot, which plots the significance (usually -log10 p-value) against the magnitude of change (usually log2 fold change).
benjamin_rose_author
Wed Jan 01 2025
These Z-scores provide a statistical measure of how different a gene's expression is from the norm.
FireflySoul
Wed Jan 01 2025
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