What does STAT3 regulate?
I'm interested in understanding the regulatory functions of STAT3. Specifically, I want to know what biological processes or molecules are influenced by STAT3.
What is STAT1 STAT3 gain of function and mechanisms of immune dysregulation?
STAT1 and STAT3 are members of the STAT family of transcription factors. Gain-of-function mutations in these genes lead to immune dysregulation by altering their normal regulatory roles. Specifically, such mutations can result in enhanced or abnormal activation of immune responses, contributing to the development of immune-related diseases.
What inhibits STAT3?
I'm interested in understanding what factors or substances can inhibit the activity of STAT3. I'm looking for specific inhibitors that can regulate or suppress the function of STAT3.