Questions tagged [stat1]

Riccardo Thu Oct 31 2024 | 7 answers 1782

I'm trying to understand the activation process of STAT1. I want to know what factors or molecules can trigger the activation of STAT1 in a biological context.

EmmaWatson Thu Oct 31 2024 | 6 answers 1202

I'm interested in understanding the function of STAT1 gene. Specifically, I want to know which genes are activated by STAT1.

CryptoWizardry Thu Oct 31 2024 | 6 answers 1089

STAT1 is a gene located on chromosome 2, encoding a protein that is a member of the STAT protein family. STAT1 plays a key role in signal transduction and transcriptional activation, involved in various biological processes such as cell apoptosis, proliferation, and immune response.

Margherita Thu Oct 31 2024 | 7 answers 1326

I am wondering about the location of STAT1. I want to know where it can be found.

Federica Wed Oct 30 2024 | 5 answers 1208

STAT1 and STAT3 are members of the STAT family of transcription factors. Gain-of-function mutations in these genes lead to immune dysregulation by altering their normal regulatory roles. Specifically, such mutations can result in enhanced or abnormal activation of immune responses, contributing to the development of immune-related diseases.